CONTACTS
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Phone: (706) 721-3403
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Email: spurohit@mail.mcg.edu
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Room: CA4095
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Address:
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| Medical College of Georgia, |
| CBGM, 1120 15th Street, |
| CA4120, |
| Augusta, GA 30912 |
| MCG Faculty Page |
EDUCATION
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| Ph.D., Molecular Reproduction |
| Devi Ahilya University |
| M.S., Biochemistry |
| Nagpur University |
| B.S., Biochemistry |
| Nagpur University |
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SHARAD PUROHIT:
ASSISTANT PROFESSOR
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Research Areas
Proteomic and bioinformatics approaches for identification of protein markers leading to the loss of cellular homeostasis in human diseases.
Molecular networks of signaling cascades driven by protein(s) for the regulation of cellular process in health and disease.
In vivo cellular signaling events as an intimate product of the local cellular ecology, cell-cell interaction and cell matrix interaction, includes the influence of soluble factors and post-translational modifications of proteins.
High-throughput screening of parent libraries for small molecules to identify drug targets for treatment/therapy of type-1 diabetes
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Identification and validation of serum biomarkers for T1D
The aim of proposed study is to identify diabetes associated differences in serum proteins and their potential in prediction of type 1 diabetics in young.
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Identification and validation of serum biomarkers for T1D
The research proposal is aimed to study the temporal changes in levels of IL-1ra and MIP-1b during the time course of progression of antibody negativity to development of antibodies to pancreatic autoantigens, resulting in type-1 diabetes.
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Cadmium reduces nitric oxide production by impairing phosphorylation of endothelial nitric oxide synthase.
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Majumder S, Muley A, Kolluru GK, Saurabh S, Tamilarasan KP, Chandrasekhar S, Reddy HB, Purohit S, Chatterjee S.
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Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
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Assessing the utility of SELDI-TOF and model averaging for serum proteomic biomarker discovery.
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Purohit S, Podolsky R, Schatz D, Muir A, Hopkins D, Huang YH, She JX.
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Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
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The application of genomic and proteomic technologies in predictive, preventive and personalized medicine.
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Collins CD, Purohit S, Podolsky RH, Zhao HS, Schatz D, Eckenrode SE, Yang P, Hopkins D, Muir A, Hoffman M, McIndoe RA, Rewers M, She JX.
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Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 1120 15th Street, CA4124, Augusta, GA 30912-2400, United States.
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Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes.
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Purohit S, Podolsky R, Collins C, Zheng W, Schatz D, Muir A, Hopkins D, Huang YH, She JX.
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Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA 30912, USA
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A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes.
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Guo D, Li M, Zhang Y, Yang P, Eckenrode S, Hopkins D, Zheng W, Purohit S et al
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Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 1120 15th Street, CA4098, Augusta, Georgia 30912, USA.
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