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Robert Podolsky, Ph.D.

CONTACTS

Phone: (706) 721-6335
Email: RPODOLSKY@MCG.EDU
Room: CA 4094
Address:
Medical College of Georgia,
CBGM, 1120 15th Street,
CA 4094,
Augusta, GA 30912
MCG Faculty Page


EDUCATION


Ph.D.,
University of California, Riverside
 
BS,
University of California, Riverside
ROBERT PODOLSKY:
       ASSISTANT PROFESSOR
Research Areas
My research focuses on understanding how genes and gene products work together with environmental factors in relation to diseases.  The main focus of this work is statistical and focuses on three main areas:
  • Methods for prioritizing genes or proteins of interest from high-throughput experiments;
  • Methods for identifying and developing genetic and genomic biomarkers for disease prediction, disease classification and diagnosis, and identifying appropriate therapies;
  • Methods for inferring functional sets of genes that have been modified in the disease state.
My research currently involves several diseases including type 1 diabetes and obesity.
 

RESEARCH PROJECTS
Development of microarray-based biomarkers for type 1 diabetes
This grant is to develop predictive markers for type 1 diabetes using microarray technology. Responsibility: Analyze data for the entire project and develop statistical methods to identify predictive markers.  
Proteomic changes/progression of human type 1 diabetes
This grant is to develop predictive markers for type 1 diabetes using proteomic technology. Responsibility: Analyze data for the entire project and develop statistical methods to identify predictive markers.  
Laser Capture Microscopy and 2D-DIGE: Cancer Proteomics
The major goal of this research is to apply 2D-DIGE technology for the identification of biomarkers characteristic of the progression of four target neoplasms: cervical, esophageal, gastric and colon. Responsibility: Analyze data for the entire project.  
Coordinating and Bioinformatics Unit of the Mouse Models of Diabetic Complications Consortium - Thursday, August 13, 2009
This grant is to provide bioinformatic and organizational support for a consortium.  My role on this project is contributing statistical support and helping to develop statistical aspects of the web portal for the consortium.
 

Analysis of CD4+ T lymphocyte subsets and their function in anti-tumor immune response. - Thursday, August 13, 2009
This grant is to identify different T lymphocyte subsets and to chracterize their function.  My role on this project is to provide statistical bioinformatics support and to provide statistical support in identifying subsets.  
  

PUBLICATIONS
Effect of comorbidity on quality of life and treatment selection in patients with squamous cell carcinoma of the head and neck.
Gourin CG, McAfee WJ, Neyman KM, Howington JW, Podolsky RH, Terris DJ
Department of Otolaryngology-Head and Neck Surgery, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, U.S.A. cgourin@mcg.edu
Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene.
Wang CY, Podolsky R, She JX
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA. cwang@mcg.edu
Assessing the utility of SELDI-TOF and model averaging for serum proteomic biomarker discovery.
Purohit S, Podolsky R, Schatz D, Muir A, Hopkins D, Huang YH, She JX
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
The application of genomic and proteomic technologies in predictive, preventive and personalized medicine.
Collins CD, Purohit S, Podolsky RH, Zhao HS, Schatz D, Eckenrode SE, Yang P, Hopkins D, Muir A, Hoffman M, McIndoe RA, Rewers M, She JX
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 1120 15th Street, CA4124, Augusta, GA 30912-2400, United States.
Racial disparities in patients with head and neck squamous cell carcinoma.
Gourin CG, Podolsky RH
Department of Otolaryngology-Head and Neck Surgery, and the Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, Georgia 30912-4060, USA. cgourin@mcg.edu
ParaKMeans: Implementation of a parallelized K-means algorithm suitable for general laboratory use.
Kraj P, Sharma A, Garge N, Podolsky R, McIndoe RA
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA USA.
The IL-10 and IFN-gamma pathways are essential to the potent immunosuppressive activity of cultured CD8+ NKT-like cells.
Zhou L, Wang H, Zhong X, Jin Y, Mi QS, Sharma A, McIndoe RA, Garge N, Podolsky R, She JX.
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, 15th Street, Augusta, GA 30912, USA.
IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells.
Liu S, Wang H, Jin Y, Podolsky R, Reddy MV, Pedersen J, Bode B, Reed J, Steed D, Anderson S, Yang P, Muir A, Steed L, Hopkins D, Huang Y, Purohit S, Wang CY, Steck AK, Montemari A, Eisenbarth G, Rewers M, She JX.
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
Effect of comorbidity on post-treatment quality of life scores in patients with head and neck squamous cell carcinoma.
Gourin CG, Boyce BJ, Vaught CC, Burkhead LM, Podolsky RH.
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21287, USA.
Candidate genes and growth curves for adiposity in African- and European-American youth.
Podolsky RH, Barbeau P, Kang HS, Zhu H, Treiber FA, Snieder H.
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA 30912, USA.
A mixture model approach to the tests of concordance and discordance between two large-scale experiments with two-sample groups.
Lai Y, Adam BL, Podolsky R, She JX.
Department of Statistics and Biostatistics Center, The George Washington University, 2140 Pennsylvania Avenue, N.W. Washington, DC 20052, USA.
A modified hyperplane clustering algorithm allows for efficient and accurate clustering of extremely large datasets.
Sharma A, Podolsky R, Zhao J, McIndoe RA.
Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA, USA.
  

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